Mass Spectrometry Positions


Please forward job vacancies for posting to Kerry Peru


Posting Date:  January 20/2010

Technical Officer, Mass Spectrometry Facility
Saskatoon, SK

 
An exciting opportunity exists for a skilled bioanalytical chemist in the mass spectrometry facility at the Plant Biotechnology Institute.  The facility works on a wide variety of projects from PBI/NRC research groups and external clients resulting in a diverse set of everyday challenges. 

Under the direction of the Research Council Officer, the Technical Officer will be responsible for developing and implementing new LC-MS and LC-MS/MS methods using a variety of state of the art instrumentation including, among others, UPLC, Q-TOF/MS/MS, and MALDI-MS/MS.  He/she will be an expert in the development and optimization of sample handling and preparation protocols, responsible for developing methods for separation, identification, and quantitation of small molecules in complex mixtures.  The successful candidate will also have a background working with metabolomic (and ideally also proteomic) workflows.

Because of the diverse nature of the research at the facility, the position requires co-operation with the other laboratory staff on fundamental and applied research in mass spectrometry and also the ability to effectively communicate with researchers and external clients.  In addition, the successful candidate must also be a problem solver; able to apply their experiences to solve new challenges and produce high quality results in a timely fashion. 

He/she will also be expected to deliver oral and poster presentations, contribute to  the preparation of manuscripts for publication, provide training to industrial partners, students, and others on the application and use of techniques in the facility, and to perform other duties as required.
 
Minimum requirement:  B.Sc.
 
To apply, please refer to the following website: http://www.nrc-cnrc.gc.ca/careers/jobpost.nsf/EnglishAll/CEFE496DE7D5A544852576AF00549953
 
Closing date: Feb. 10, 2010


Posting Date: January 18/2010

Research assistant, graduate students in the analysis of DNA damage by mass spectrometry


We are looking for a research assistant to develop new procedures for the analyses of modified “damaged” DNA base and sugar components using LC-MS/MS. Preferably, the candidate should have previous experience with Sciex MS software and instrumentation. We will also consider graduate students and post-doctorate fellows interested in this area of research.

Free radicals constantly challenge DNA integrity. Free radicals are produced in copious amounts by biological processes, such as oxidative phosphorylation and inflammation. They are also generated at toxic levels by ionizing radiation (X-rays and charged particles), ultraviolet light, and certain xenobiotics. The constant formation of DNA damage and lack of efficient DNA repair is a major contributor to cancer and other disorders. Using chemical approaches, we aim to measure novel types of DNA damage and assess their biological processing.

Minimum requirement: B.Sc.

Applicants should send a cover letter and CV.

J. Richard Wagner, Ph.D.

Department of Nuclear Medicine and Radiobiology
Faculty of Medicine and Health Sciences
University of Sherbrooke,
Sherbrooke (Quebec) J1H 5N4
Email: richard.wagner@usherbrooke.ca
Web: http://www.usherbrooke.ca/mednuc




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